tag:blogger.com,1999:blog-3125132926699584358.post2482243824521471552..comments2024-03-18T22:10:40.998-05:00Comments on Family Dysfunction and Mental Health Blog: Latuda and Bipolar DepressionDavid M. Allen M.D.http://www.blogger.com/profile/06280912088483192599noreply@blogger.comBlogger7125tag:blogger.com,1999:blog-3125132926699584358.post-39029504724125686562014-04-17T22:42:38.382-05:002014-04-17T22:42:38.382-05:00I've seen stories that say that some people le...I've seen stories that say that some people leave the FDA and go to work for Pharma and vice versa - much like with the SEC and Goldman Sachs - but I haven't researched the issue to know for sure whether the stories are true or, if true, how big the problem is. I wouldn't be at all surprised if there's a bunch of foxes in the henhouse.David M. Allen M.D.https://www.blogger.com/profile/06280912088483192599noreply@blogger.comtag:blogger.com,1999:blog-3125132926699584358.post-2615540490717357672014-04-17T20:49:57.272-05:002014-04-17T20:49:57.272-05:00David, thank you for being a stalwart in exposing ...David, thank you for being a stalwart in exposing these ludicrous claims...Abilify and Latuda indicated for depression?! Bipolar or unipolar...makes no sense that blocking dopamine can relieve depression. Even a "partial agonist" (as BMS claims of Abilify) is more of an antagonist on a receptor level than no drug at all. Otherwise, it probably couldn't cause TD. Your impeccable insight reminds me so much of the Hans Christian Andersen tale of the Emperor's New Clothes. Clearly as you've illustrated, the Emperor (or Emperors if you include Big Pharma and Academic Psychiatry) has no clothes. But the other issue is that the clothes have no emperor. The FDA is either incompetent or colluding with this corrupt alliance. I wonder what ties voting members have with pharmaceutical interests? Do you have any information on that? doctorzhttp://www.doctorz.netnoreply@blogger.comtag:blogger.com,1999:blog-3125132926699584358.post-30226257426774327242014-04-10T21:15:32.789-05:002014-04-10T21:15:32.789-05:00If course it's baloney on top of baloney, the ...If course it's baloney on top of baloney, the TV commercials, which saturate evening schedules, subtly emphasize that Latuda is for depression -- a lay person is going think that it's an antidepressant. Disease mongering as usual. Let the AERs and denial begin.Altostratahttp://survivingantidepressants.orgnoreply@blogger.comtag:blogger.com,1999:blog-3125132926699584358.post-55933850280690795462014-04-08T22:20:59.301-05:002014-04-08T22:20:59.301-05:00Interesting comment beneficii.
The more specifi...Interesting comment beneficii. <br /><br />The more specifically anti-dopaminergic the antipsychotic - like haloperidol - and risperidone and aripiprazole (Abiify) are similar in this regard = then the less metabolic side-effects (obesity and diabetes) but more risk extrapyramidal side-effects like akathisia, dystonias and dyskinesias (movement disorders).<br /><br />So one wonders how Latuda can be the best of both worlds? <br /><br />EPSE data can take time to accumulate and are partly dose-dependent - it'd be interesting to see the methodology of their studies. And the hidden raw data of course!<br /><br />One day (soon hopefully) we'll all have access to raw data and methodology data - www.alltrials.net <br /><br />Also we can now all report our own personal side-effects to www.rxisk.org <br /><br />Great investigative article as always David :-)Peter Parry MBBS FRANZCPhttp://www.mentalhealthacademy.com.au/author_details.php?authorid=6562noreply@blogger.comtag:blogger.com,1999:blog-3125132926699584358.post-66645090108246344902014-04-08T16:13:35.177-05:002014-04-08T16:13:35.177-05:00For me, Latuda was great for about a month, but fo...For me, Latuda was great for about a month, but for some reason after being a month on it, I started experiencing severe akathisia, which forced me to stop it.beneficiihttps://www.blogger.com/profile/08107436044843445219noreply@blogger.comtag:blogger.com,1999:blog-3125132926699584358.post-36284549007046981972014-04-08T13:07:05.982-05:002014-04-08T13:07:05.982-05:00Maybe not, but the three newest antipsychotics are...Maybe not, but the three newest antipsychotics are more like Abilify and Rispirdal, which do in fact have a MUCH lower incidence of metabolic syndrome than seroquel and zyprexa. That is a fact. All of the so-called "atypicals" have a considerably lower incidence of tardive than the phenothiazines and Haldol, but that's not to say it does not occur with all of them. That's where close follow up comes in.David M. Allen M.D.https://www.blogger.com/profile/06280912088483192599noreply@blogger.comtag:blogger.com,1999:blog-3125132926699584358.post-78040438605503768462014-04-08T12:46:52.423-05:002014-04-08T12:46:52.423-05:00Do you really believe Latuda will turn out to have...Do you really believe Latuda will turn out to have a low incidence of metabolic syndrome and tardive dyskinesia? Have these claims ever been made before for an atypical antipsychotic and proven wrong? <br /><br />Despite the FDA, Sunovion reps are phoning doctors and making the claims of Latuda's superiority. The TV ad campaign alone should alert all that something is very fishy about Latuda. It looks like Sunovion is trying to cash in before the adverse effects hit the fan.<br /><br />See http://1boringoldman.com/index.php/2014/02/14/or-both/<br /><br />http://1boringoldman.com/index.php/2014/02/15/creepy/<br /><br />http://thoughtbroadcast.com/2011/10/02/latuda-palooza-marketing-or-education/<br /><br />http://thelastpsychiatrist.com/2011/10/the_rise_and_fall_of_atypical.htmlAltostratahttp://survivingantidepressants.orgnoreply@blogger.com